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Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.
| Molecular Weight | 492.14 |
| Formula | C18H14Cl4N4O4 |
| CAS Number | 64211-46-7 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage | 4°C, dry, sealed |
| Related Antifungal Products |
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| SDH-IN-1
SDH-IN-1 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. |
| Averantin
Averantin is the minor metabolite of the fungus Cercospora arachidicola. |
| Flutolanil
Flutolanil is a broad-spectrum fungicide. |
| Datiscetin
Datiscetin is a natural compound isolated from the cultivar “Roland”, and shows fungitoxic activity towards F. |
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