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Nikkomycin Z, a nucleoside-peptide, is a selective competitive chitin synthesis inhibitor. Nikkomycin Z has antifungal effects and acts as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine.
| Molecular Weight | 495.44 |
| Formula | C20H25N5O10 |
| CAS Number | 59456-70-1 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 31.25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Wei Chen, et al. Nature. Structural basis for directional chitin biosynthesis
[5] David J Larwood. J Fungi (Basel). Nikkomycin Z-Ready to Meet the Promise?
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