About 5 results found for searched term "UT-155" (0.118 seconds)
Cat.No. | Name | Target |
---|---|---|
M14623 | UT-155 | Androgen Receptor |
UT-155 is a selective and potent androgen receptor (AR) antagonist, with a Ki of 267 nM for UT-155 binding to AR-LBD. | ||
M29116 | (R)-UT-155 | Androgen Receptor |
(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer. | ||
M3484 | Dolutegravir | Integrase |
GSK1349572 | ||
Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. | ||
M9200 | Ibodutant | Neurokinin Receptor |
MEN15596 | ||
Ibodutant (MEN15596) is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1. | ||
M28302 | SR1555 | ROR |
SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ (RORγ) inverse agonist with an IC50 value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases. |
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