About 2 results found for searched term "Thiorphan" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20002 | Thiorphan | Neprilysin (NEP) |
| Neprilysin/neutral endopeptidase inhibitor | ||
| Thiorphan was a selective neprilysin inhibitor with an IC50 value of 6.9 nM. Increased bradykinin-induced relaxation of isolated porcine coronary rings with potassium chloride precontraction under hypoxic but very oxygen conditions. | ||
| M3582 | Racecadotril | Neprilysin (NEP) |
| Acetorphan | ||
| Racecadotril is a peripheral enkephalinase inhibitor with an IC50 of 4.5 μM.Racecadotril and its active metabolite, Thiorphan, inhibited the activity of purified NEP in the mouse brain with Ki's of 4500 and 6.1 nM.May be used in diarrhea related studies. | ||
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