Free shipping on all orders over $ 500


Cat. No. M3582
Racecadotril Structure


Size Price Availability Quantity
200mg USD 60  USD60 In stock
1g USD 100  USD100 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM. Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 385.48
Formula C21H23NO4S
CAS Number 81110-73-8
Purity >98%
Solubility DMSO 20 mg/mL
Ethanol 70 mg/mL
Storage at -20°C

[1] Marion Eberlin, et al. Racecadotril in the treatment of acute diarrhea in children: a systematic, comprehensive review and meta-analysis of randomized controlled trials

[2] Morris Gordon, et al. Racecadotril for acute diarrhoea in children: systematic review and meta-analyses

[3] No authors listed. Drug Ther Bull. What place for ▾racecadotril?

[4] A J Matheson, et al. Racecadotril

[5] J C Schwartz. Racecadotril: a new approach to the treatment of diarrhoea

Related Opioid Receptor Products
Ro 64-6198

Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC50 value of 25.6 nM.

Norbinaltorphimine dihydrochloride

Norbinaltorphimine dihydrochloride is a potent and selective κ opioid receptor antagonist.

Methylnaltrexone Bromide

Methylnaltrexone Bromide, a quaternary derivative of Naltrexone, is an orally active and selective mu-opioid receptor antagonist, functions as a peripherally acting receptor antagonist in tissues of the gastrointestinal tract.


Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and u-receptor agonist.


Aticaprant (CERC-501) is a potent and centrally-penetrant kappa opioid receptor antagonist with a Ki of 0.807 nM.

Abmole Inhibitor Catalog

Keywords: Racecadotril, Acetorphan supplier, Opioid Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.