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Omapatrilat is a vasopeptidase inhibitor, a dual metalloprotease inhibitor of neutral endopeptidase (NEP, neprilysin) and angiotensin converting enzyme (ACE). Omapatrilat is a highly potent antihypertensive agent, but was not approved to treat hypertension because of increased incidence of angioedema.
| Molecular Weight | 408.53 |
| Formula | C19H24N2O4S2 |
| CAS Number | 167305-00-2 |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Scott A Hubers, et al. Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition
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