About 5 results found for searched term "Temozolomide" (0.14 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2129 | Temozolomide | DNA/RNA Synthesis |
| NSC362856; CCRG81045; TMZ | ||
| Temozolomide (TMZ) is an oral DNA methylating, chemotherapeutic agent. | ||
| M27834 | Temozolomide acid | DNA/RNA Synthesis |
| Temozolomide acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid has an activity similar to the parent compound Temozolomide with the same anticancer activity. | ||
| M30213 | AR03 | DNA/RNA Synthesis |
| BMH-23 | ||
| AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells. | ||
| M41282 | 5-NIdR | Apoptosis |
| 5-NIdR (1-(β-D-2-Deoxyribofuranosyl)-5-nitroindole), an artificial nucleoside, exhibits the ability to inhibit the replication of DNA lesions generated by Temozolomide. | ||
| M56624 | MTIC | Metabolite/Endogenous Metabolite |
| MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. | ||
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