About 7 results found for searched term "TRAP1-IN-1" (0.161 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41512 | TRAP1-IN-1 | HSP |
| TRAP1-IN-1 is a potent and selective inhibitor of TRAP1, a mitochondrial isoform of Hsp90. | ||
| M13710 | iRucaparib-AP6 | PARP |
| iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. | ||
| M18062 | 3-Hydroxy-9,10-dimethoxyptercarpan | VEGFR/PDGFR |
| Methylnissolin; Astrapterocarpan | ||
| Methylnissolin (Astrapterocarpan) inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. | ||
| M24570 | Dalantercept | TGF-beta/Smad |
| ACE-041 | ||
| Dalantercept (ACE-041) is an activin receptor like kinase 1 (ALK1) inhibitor, a ligand trap for bone morphogenetic proteins (BMP) 9 and BMP 10. Dalantercept reduces tumor angiogenesis and delays tumor growth by binding to BMP 9 and BMP 10. As an anti angiogenic agent, Dalantercept has potential applications in persistent or recurrent ovarian cancer, renal cell carcinoma (RCC), and related malignant tumors. | ||
| M27954 | CBK289001 | PAR |
| CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively. | ||
| M41509 | TRAP1-IN-2 | HSP |
| TRAP1-IN-2 is a selective TRAP1 client protein degrader, while TRAP1-IN-2 is useless for Hsp90-cytosolic clients. | ||
| M52919 | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | PAR |
| Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD). | ||
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