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iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1.
Molecular Weight | 886.96 |
CAS Number | 2410557-00-3 |
Solubility (25°C) | DMSO 50 mg/mL |
Storage | -20°C, sealed |
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