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iRucaparib-AP6

Cat. No. M13710

All AbMole products are for research use only, cannot be used for human consumption.

iRucaparib-AP6 Structure

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Quality Control & Documentation
Biological Activity

iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach. iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1.

Chemical Information
Molecular Weight 886.96
CAS Number 2410557-00-3
Solubility (25°C) DMSO 50 mg/mL
Storage -20°C, sealed
References

[1] Shuai Wang, et al. Nat Chem Biol. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation

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  Catalog
Abmole Inhibitor Catalog




Keywords: iRucaparib-AP6 supplier, PARP, inhibitors, activators

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