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Dalantercept (ACE-041) is an activin receptor like kinase 1 (ALK1) inhibitor, a ligand trap for bone morphogenetic proteins (BMP) 9 and BMP 10. Dalantercept reduces tumor angiogenesis and delays tumor growth by binding to BMP 9 and BMP 10. As an anti angiogenic agent, Dalantercept has potential applications in persistent or recurrent ovarian cancer, renal cell carcinoma (RCC), and related malignant tumors.
| CAS Number | 1186210-24-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[5] Shilpa Gupta, et al. Curr Oncol Rep. Activin receptor inhibitors--dalantercept
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