About 3 results found for searched term "TH-Z145" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55216 | TH-Z145 | Antibiotic |
| THZ145 | ||
| TH-Z145 is a lipophilic GGPPS inhibitor (GGPPS IC50 = 210 nM). TH-Z145 is a very lipophilic bisphosphonate that lacks the cationic center essential for FPPS inhibition and is thus a specific GGPPS inhibitor (FPPS IC50 >30 mM). TH-Z145 exhibited strong prophylactic effects in a pathogenic influenza model. | ||
| M3479 | Aripiprazole | 5-HT Receptor |
| OPC-14597 | ||
| Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. Aripiprazole (OPC-14597) is a potent and high-affinity dopamine D2 receptor partial agonist. | ||
| M8654 | AA-CW236 | Others |
| AA-CW236 is a cell-permeable chloromethyl triazole (CMT) derivative that acts as a non-pseudosubstrate inhibitor against human O(6)-alkylguanine DNA methyltransferase (MGMT) by targeting MGMT active site Cys145 for covalent modification (KI = 24 nM, kinact = 0. | ||
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