About 4 results found for searched term "Sigma Receptor" (0.084 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14060 | CT1812 | Sigma Receptor |
| Sigma-2 receptor antagonist 1 | ||
| CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant sigma-2 (σ-2) receptor antagonist with a Ki of 8.5 nM. | ||
| M28755 | Sigma-1 receptor antagonist 1 | Sigma Receptor |
| Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor (Ki = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain. | ||
| M42693 | Sigma-1 receptor antagonist 4 | Sigma Receptor |
| Sigma-1 receptor antagonist 4 is a potent σ1R antagonist that significantly enhances the analgesic effect of morphine and rescues morphine-induced analgesic tolerance. | ||
| M42704 | Sigma-1 receptor antagonist 5 | Sigma Receptor |
| Sigma-1 receptor antagonist 5 and histamine H3 (hH3R, Ki=7.7 nM, IC50=215 nM). | ||
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