About 2 results found for searched term "SPR inhibitor 3" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28121 | SPR inhibitor 3 | Others |
| SPRi3 | ||
| SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels. | ||
| M28299 | SPR719 | Topoisomerase |
| VXc-486 | ||
| SPR719 (VXc-486) is a gyrase B inhibitor, with bactericidal activity. SPR719 potently inhibits multiple agent-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively. | ||
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