About 8 results found for searched term "SF-22" (0.162 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3782 | Oxiracetam | 5-HT Receptor |
| ISF 2522 | ||
| Oxiracetam could decrease neural injury and increase ability of learning, memory and space cognition in traumatic brain injury rats. | ||
| M8175 | SF-22 | Others |
| Radioligand studies reveal that SF-22 also targets 5-HT2B and 5-HT6 serotonin receptors and dopamine transporter. | ||
| M5354 | (R)-Oxiracetam | Others |
| (R)-(+)-Oxiracetam | ||
| (R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant. | ||
| M10985 | γ-Oryzanol | DNA Methyltransferase |
| γ-Oryzanol effectively inhibits DNA methyltransferases (DNMTs) in mouse striatum. Suppression of DNMT1 and DNMT3a,IC50 3.2 μM and 22.3 μM, respectively. | ||
| M21389 | JNJ-55511118 | Others |
| JNJ-55511118 is an AMPA receptor negative regulator containing transmembrane AMPA receptor regulatory protein γ8 (TARP-γ8). 1 It inhibits glutamate-induced calcium flux in HEK293F cells that were cotransfected with TARP-γ8 and GluA1o, GluA1i, GluA2i, GluA3o, or GluA4o (IC50s = 11.22, 12.3, 7.41, 38.02, and 15.85 nM, respectively). | ||
| M21429 | Recombinant Human SDF-1β/CXCL12 (E. coli) | Cytokines and Growth Factors |
| SDF1β; SDF-1 beta; CXCL-12 | ||
| Stromal cell-derived factor-1β (SDF-1β), also known as SCYB12, PBSF, and CXCL12, is an 8.3 kDa, heparin-bound member of the CXC(or α) chemokine family that signals via the CXCR4 receptor. Protein Construction: SDF-1β/CXCL12 (Lys22-Met93). Accession # P48061. | ||
| M29174 | CHMFL-ABL/KIT-155 | Src-bcr-Abl |
| CHMFL-ABL-KIT-155 | ||
| CHMFL-ABL/KIT-155 (CHMFL-ABL-KIT-155; compound 34) is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s of 46 nM and 75 nM, respectively), and it also presents significant inhibitory activities to BLK (IC50=81 nM), CSF1R (IC50=227 nM), DDR1 (IC50=116 nM), DDR2 (IC50=325 nM), LCK (IC50=12 nM) and PDGFRβ (IC50=80 nM) kinases. | ||
| M58581 | MS4322 | PROTAC |
| YS43-22 | ||
| MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. | ||
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