About 12 results found for searched term "SD-6" (0.08 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2870 | MSDC-0160 | Others |
| Mitoglitazone; CAY10415 | ||
| MSDC 0160 (Mitoglitazone) is an insulin sensitizer that regulates the mitochondrial target of thiazolidinedione (mTOT) and a regulator of mitochondrial pyruvate vector (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has potential for use in Alzheimer's disease. | ||
| M7558 | SD-06 | p38 MAPK |
| SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). IC50 value: 170 nM Target: p38MAPK | ||
| M5748 | Azemiglitazone | PPAR |
| MSDC-0602; MSDC0602 | ||
| Azemiglitazone (MSDC-0602) is a PPARγ -retained thiazolidindione (TZD) that interacts with mitochondrial pyruvate vector (MPC) and inhibits its activity. | ||
| M21159 | SD-36 | PROTAC |
| SD-36 is a potent STAT3 PROTAC degradation agent (Kd=~50 nM) with a high selectivity compared to other STAT members. SD-36 is composed of the STAT3 inhibitor SI-109, a linker, and an analog of Cereblon ligand Lenalidomide for E3 ubiquitin ligase. | ||
| M28792 | SD-169 | p38 MAPK |
| SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC50 of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC50 of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation. | ||
| M30982 | DPI 201-106 | Sodium Channel |
| SDZ 201106 | ||
| DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect. | ||
| M40989 | Azemiglitazone potassium | PPAR |
| MSDC-0602K | ||
| Azemiglitazone potassium is a thiazolidinediones that binds to PPARγ with an IC50 value of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M41148 | SDH-IN-6 | Antifungal |
| SDH-IN-6 is a potent succinate dehydrogenase (SDH) inhibitor. | ||
| M41683 | LSD1-IN-26 | Histone demethylase |
| LSD1-IN-26 is a potent LSD1 inhibitor, with an IC50 of 25.3 nM. | ||
| M42646 | SD-6 | AChR/AChE |
| SD-6 is an orally active inhibitor of hAChE and hBChE with IC50 values of 0.907 µM and 1.579 µM, respectively. | ||
| M59739 | SUSD6 Human Pre-designed siRNA Set | siRNA |
| Human SUSD6 Pre-designed siRNA Set contains three designed siRNAs for SUSD6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 9766 | ||
| M60230 | SDR16C5 Human Pre-designed siRNA Set | siRNA |
| Human SDR16C5 Pre-designed siRNA Set contains three designed siRNAs for SDR16C5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 195814 | ||
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