About 2 results found for searched term "S1RA" (0.142 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2596 | S1RA | Sigma Receptor |
| E-52862 | ||
| S1RA (E-52862) is a potent and selective sigma-1 receptor (σ1R, Ki=17 nM), which showes good selectivity against σ2R (Ki > 1000 nM). | ||
| M28096 | S1RA hydrochloride | Sigma Receptor |
| E-52862 hydrochloride | ||
| S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization. | ||
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