About 12 results found for searched term "Ryanodine" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7234 | Ryanodine | Others |
| Ryanodine is a ca2+ release inhibitor. | ||
| M9272 | S107 | Others |
| S107 free base | ||
| S107 is a Type 1 ryanodine receptor (RyR1) stabilizer. | ||
| M27682 | JTV-519 | Calcium Channel |
| K201 | ||
| JTV-519 (K201) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. | ||
| M28431 | JTV-519 hemifumarate | Calcium Channel |
| K201 hemifumarate | ||
| JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. | ||
| M28494 | JTV-519 free base | Calcium Channel |
| K201 free base | ||
| JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. | ||
| M30183 | Chlorantraniliprole | Others |
| Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ∼300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM). | ||
| M30543 | Dantrolene | Others |
| F 368 | ||
| Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome. | ||
| M49397 | ATX-II TFA | Sodium Channel |
| ATX-II TFA, a specific Na+ channel modulator toxin derived from sea anemone (Anemonia sulcata) venom, causes sensitization of cell cultures to Na+Halothane , Caffeine, and Ryanodine. In addition, ATX-II induces pulmonary venous arrhythmias and atrial fibrillation. | ||
| M52796 | Verticilide | Calcium Channel |
| Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC50 value of 4.2 μM (whereas inhibition against mouse ryanodine receptors was weak (IC50=53.9 μM)). | ||
| M52798 | Maurocalcine | Calcium Channel |
| Maurocalcine is an agonist of ryanodine receptor (RyR) channel types 1, 2 and 3 with cellular permeability. | ||
| M52801 | Imperatoxin A | Calcium Channel |
| Imperatoxin A is an activator of Ca2+-release channels/ryanodine receptors (RyRs) enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. | ||
| M56965 | JTV-519 fumarate | Others |
| JTV-519 fumarate (K201 fumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. | ||
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