About 21 results found for searched term "RR6" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1661 | AZD6244 | MEK |
| Selumetinib, ARRY-142886 | ||
| AZD6244 (ARRY-142886, Selumetinib) is a potent MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nM. | ||
| M1744 | ARRY-162 (Binimetinib) | MEK |
| MEK-162; Binimetinib; ARRY-438162 | ||
| ARRY-162 (MEK-162; Binimetinib) is a selective, potent inhibitor of MEK and cellular pERK with IC50 of 12 nM and 11 nM, respectively. | ||
| M1916 | Nelarabine | DNA/RNA Synthesis |
| Arranon, 506U78 | ||
| Nelarabine is a novel purine antimetabolite antineoplastic agent. | ||
| M5873 | Pexmetinib (ARRY-614) | p38 MAPK |
| ARRY-614 | ||
| Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1. | ||
| M10476 | GDC-0575 (ARRY-575) | Checkpoint |
| RG7741; ARRY575; AK-687476 | ||
| GDC-0575 (ARRY-575, RG7741) is a potent and selective oral inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. | ||
| M13367 | Metarrestin (ML246) | DNA/RNA Synthesis |
| Metarrestin (ML246) is a first-in-class, oral active and specific perinucleolar compartment (PNC) inhibitor. It can destroy the nucleolus structure and inhibit the transcription of RNA polymerase (Pol) I. Metarrestin blocks the development of metastasis and prolongs survival in mouse cancer models. | ||
| M14171 | Selumetinib sulfate | MEK |
| AZD6244 sulfate; ARRY-142886 sulfate | ||
| Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. | ||
| M14762 | RR6 | Others |
| RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. | ||
| M21471 | Recombinant Human Transferrin (HEK293, C-6His) | Cytokines and Growth Factors |
| Serotransferrin; Transferrin; Beta-1 metal-binding globulin | ||
| Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1. | ||
| M21640 | Tinlorafenib | Raf |
| PF-07284890; ARRY-461 | ||
| Tinlorafenib (PF-07284890) is an orally active BRAF kinase inhibitor, with IC50 values of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. | ||
| M24669 | Enlimomab | Integrin |
| BI-RR 0001; Anti-Human IL6 Recombinant Antibody | ||
| Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research . | ||
| M44371 | 3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal | Others |
| 3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal | ||
| M53536 | CEF19, Epstein-Barr Virus latent NA-3A (458-466) | Anti-infection |
| CEF19, Epstein-Barr Virus latent NA-3A (458-466) is a single peptide epitope, YPLHEQHGM, representing residues 458-466 of the type 1 Epstein-Barr Virus (EBV) nuclear antigen 3A protein (B95.8 strain). | ||
| M53537 | CEF27, Epstein-Barr Virus BRLF-1 lytic (148-156) | Anti-infection |
| CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 corresponding to amino acids 148-156 of the BRLF1 protein. | ||
| M53652 | Lactoferricin H, Lactotransferrin (37-61), human | Antibiotic |
| Lactoferricin H, Lactotransferrin (37-61), human is a biological active peptide. | ||
| M54460 | Acyl Carrier Protein (ACP) (65-74) | Others |
| Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment. | ||
| M54732 | Recombinant Human GAS6 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| growth arrest-specific 6 | ||
| GAS6 (Growth arrest-specific protein 6) also known as AXL receptor tyrosine kinase ligand, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. | ||
| M54657 | CFTR corrector 6 | CFTR |
| CFTR corrector 6 is a potent cystic fibrosis transmembrane conductance regulator (CFTR) enhancer for cystic fibrosis (CF) and other CFTR-related diseases. | ||
| M54731 | Recombinant Mouse GAS6 Protein (HEK293, C-His) | Cytokines and Growth Factors |
| growth arrest-specific 6 | ||
| GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. | ||
| M54699 | Recombinant Human Lactoferrin/LTF Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| Lactotransferrin; Kaliocin-1 | ||
| Lactoferrin (LTF) is a major iron-binding protein in exocrine fluid and controls the level of free iron in the blood and external secretions. It exhibits multiple antibacterial effects by chelating iron and disrupting bacterial membranes. | ||
| M57529 | Tert-Butyl 2-Amino-4H-Pyrrolo[3,4-D]Thiazole-5(6H)-Carboxylate | Others |
| Tert-Butyl 2-Amino-4H-Pyrrolo[3,4-D]Thiazole-5(6H)-Carboxylate | ||
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