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About 8 results found for searched term "R-406" (0.033 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M1767 | R-406 | R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM. |
| M7534 | SSR240612 | Treatment with the kinin B1 receptor antagonist, SSR240612, provided a protective effect against organ damage by interfering with multiple target functions, including the suppression of B1R-induced inflammation and platelet aggregation. |
| M9924 | Risdiplam | Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues. |
| M13549 | Xevinapant hydrochloride | Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). |
| M14916 | R406 besylate | R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. |
| M14917 | Fostamatinib disodium hexahydrate | Fostamatinib (R788) disodium hexahydrate is the oral prodrug of the active compound R406. |
| M21645 | Tipranavir | Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM. |
| M22506 | Recombinant Human ANGPTL4 (Mammalian, N-6His) | Recombinant Human Angiopoietin Like Protein 4 is produced by Mammalian expression system and the target gene encoding Pro166-Ser406 is expressed with a 6His tag at the N-terminus. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). |
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