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 About 8 results found for searched term "R-406" (0.033 seconds)

Cat.No.  Name Information
M1767 R-406 R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM.
M7534 SSR240612 Treatment with the kinin B1 receptor antagonist, SSR240612, provided a protective effect against organ damage by interfering with multiple target functions, including the suppression of B1R-induced inflammation and platelet aggregation.
M9924 Risdiplam Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues.
M13549 Xevinapant hydrochloride Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs).
M14916 R406 besylate R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value.
M14917 Fostamatinib disodium hexahydrate Fostamatinib (R788) disodium hexahydrate is the oral prodrug of the active compound R406.
M21645 Tipranavir Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM.
M22506 Recombinant Human ANGPTL4 (Mammalian, N-6His) Recombinant Human Angiopoietin Like Protein 4 is produced by Mammalian expression system and the target gene encoding Pro166-Ser406 is expressed with a 6His tag at the N-terminus. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity).

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