About 7 results found for searched term "Quin C1" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3238 | 4-Quinazolinamine | EGFR/HER2 |
| 4-Aminoquinazoline, NSC 288012 | ||
| 4-Quinazolinamine (4-Aminoquinazoline) is a potent and highly selective EGFR tyrosine kinase inhibitor. | ||
| M4184 | Cynarin | PI3K |
| 1,3-O-Dicaffeoylquinic acid; 1,5-Dicaffeoylquinic acid | ||
| 1, 3-dicaffeoylquinic acid is a derivative of caffeyl quinic acid, which has antioxidant activity and free radical scavenging activity. | ||
| M4941 | Lomefloxacin | Antibiotic |
| Maxaquin,SC47111A | ||
| Lomefloxacin (SC47111A) is a fluoroquinolone antibiotic. | ||
| M7176 | Quin C1 | Others |
| Quin C1 is a potent and selective FPR2 agonist. | ||
| M14448 | Echinomycin | HIF |
| Quinomycin A; NSC-13502 | ||
| Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM. | ||
| M14591 | (+)-DHMEQ | Keap1-Nrf2 |
| (1R,2R,6R)-Dehydroxymethylepoxyquinomicin; (1R,2R,6R)-DHMEQ | ||
| (+)-DHMEQ is an activator of antioxidant transcription factor Nrf2. (+)-DHMEQ is the enantiomer of (-)-DHMEQ. (-)-DHMEQ inhibits NF-kB than its enantiomer (+)-DHMEQ. | ||
| M27669 | E1231 | Sirtuin |
| 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one | ||
| E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases. | ||
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