About 6 results found for searched term "Porcupine" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10124 | Porcupine-IN-1 | Porcupine |
| Porcn-IN-1 | ||
| Porcupine-IN-1 is a potent porcupine inhibitor with IC50 value of 0.5±0.2 nM. | ||
| M8386 | IWP-3 | Others |
| IWP-3 is a Wnt inhibitor that prevents palmitylation of Wnt proteins by Porcupine (Porcn). | ||
| M8715 | GNF-1331 | Others |
| GNF-1331 is an orally available, potent and selective Porcupine (PORCN) inhibitor. | ||
| M10823 | GNF-6231 | Others |
| GNF-6231 is a strong, selective, oral-capable Porcupine inhibitor capable of blocking the Wnt signaling pathway. | ||
| M30489 | IWP-12 | Transferase |
| IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM. | ||
| M45318 | Zamaporvint | Wnt/beta-catenin |
| RXC004 | ||
| Zamaporvint is an orally active, selective Wnt inhibitor that targets the membrane-bound o-acyltransferase porcupine and inhibits Wnt ligand palmitoylation, secretion and pathway activation. In addition, Zamaporvint displays potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. It can be used in cancer-related studies. | ||
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