About 9 results found for searched term "PCSK9" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M15098 | Recombinant Human PCSK9 (HEK293,C-6His) | Cytokines and Growth Factors |
| Proprotein Convertase Subtilisin/Kexin Type 9 | ||
| Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. Accession #: Q8NBP7. | ||
| M21547 | Recombinant Mouse PCSK9 (HEK293, C-6His) | Cytokines and Growth Factors |
| Proprotein Convertase Subtilisin/Kexin Type 9 | ||
| Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in neural development. | ||
| M42608 | PCSK9-IN-15 | Serine/Threonine Protease |
| PCSK9-IN-15 is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, KD <200 nM). | ||
| M42610 | PCSK9-IN-18 | Serine/Threonine Protease |
| PCSK9-IN-18 is a potent PCSK9 inhibitor with a KD value of <200 nM. | ||
| M42612 | PCSK9-IN-14 | Serine/Threonine Protease |
| PCSK9-IN-14 is a potent PCSK9 inhibitor. | ||
| M42614 | PCSK9-IN-19 | Serine/Threonine Protease |
| PCSK9-IN-19 is a PCSK9 inhibitor. | ||
| M55020 | AZD0780 | PCSK9 |
| Laroprovstat; PCSK9-IN-12; AZD-0780 | ||
| AZD0780 (PCSK9-IN-12, EX-A6975) is an oral, potentially first-in-class small molecule inhibitor of PCSK9. AZD0780 (PCSK9-IN-12, EX-A6975) has bind affinity for PCSK9 with a Kd value of ＜200 nM. AZD0780 (PCSK9-IN-12, EX-A6975) can be used for the research of cholesterol metabolism. | ||
| M56732 | PCSK9-IN-13 | PCSK9 |
| PCSK9-IN-13(compound 3f) is a potent PCSK9 inhibitor, which can antagonize low-density lipoprotein (LDL) receptor binding by binding to PCSK9, with an IC50 of 537 nM. | ||
| M56731 | PCSK9 ligand 1 | PCSK9 |
| PCSK9 ligand 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) ligand. | ||
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