All AbMole products are for research use only, cannot be used for human consumption.
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase of the protease K family. PCSK9 binds to low density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in neural development. PCSK9 undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions.
Immobilized Recombinant Mouse PCSK9-His(Cat#M21547) at 2μg/ml (100 μl/well) can bind Biotinylated Human LDL R-His-Avi, the ED50 of Biotinylated Human LDL R-His-Avi is 0.301 ug/ml.
Recombinant Mouse Proprotein Convertase Subtilisin/Kexin Type 9 expressed the target gene encoding Gln35-Gln155&Ser156-Gln694 with a 6His tag at the C-terminus.
Accession: Q80W65
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 19&60 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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