About 7 results found for searched term "PARP1-IN-14" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41575 | PARP1-IN-14 | PARP |
| PARP1-IN-14 is a potent PARP1 inhibitor, with an IC50 of 0.6 ± 0.1 nM. | ||
| M4855 | BMN673 isomer | PARP |
| LT-674 | ||
| (8R,9S)-Talazoparib is the 8R,9S enantiomer of Talazoparib. (8R,9S)-Talazoparib is a PARP1 inhibitor with an IC50 value of 144 nM. | ||
| M10298 | AZD5305 | PARP |
| Saruparib; AZD-5305 | ||
| Saruparib (AZD5305) is a potent and oral active, second-generation PARP (highly selective PARP1) inhibitor with IC50 values of 3 nM and 1400 nM for PARP1 and PARP2, respectively. | ||
| M13712 | PARP1-IN-5 dihydrochloride | PARP |
| PARP1-IN-5 dihydrochloride is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer. | ||
| M22487 | RBN-3143 | PARP |
| RBN3143 | ||
| RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. | ||
| M29181 | PARP14 inhibitor H10 | PARP |
| PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis. | ||
| M56008 | PARP1-IN-5 | PARP |
| PARP1-IN-5 is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). | ||
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