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 About 6 results found for searched term "PARP1-IN-14" (0.186 seconds)

Cat.No.  Name Target
M41575 PARP1-IN-14 PARP
PARP1-IN-14 is a potent PARP1 inhibitor, with an IC50 of 0.6 ± 0.1 nM.
M4855 BMN673 isomer PARP
LT-674
(8R,9S)-Talazoparib is the 8R,9S enantiomer of Talazoparib. (8R,9S)-Talazoparib is a PARP1 inhibitor with an IC50 value of 144 nM.
M10298 AZD5305 PARP
Saruparib; AZD-5305
Saruparib (AZD5305) is a potent and oral active, second-generation PARP (highly selective PARP1) inhibitor with IC50 values of 3 nM and 1400 nM for PARP1 and PARP2, respectively.
M13712 PARP1-IN-5 dihydrochloride PARP
PARP1-IN-5 dihydrochloride is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer.
M22487 RBN-3143 PARP
RBN3143
RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines.
M29181 PARP14 inhibitor H10  PARP
PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.



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