All AbMole products are for research use only, cannot be used for human consumption.
PARP1-IN-5 dihydrochloride is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer.
| Molecular Weight | 537.46 |
| Formula | C25H26Cl2N2O5S |
| CAS Number | 2823308-89-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | 2-8°C, dry, sealed |
[1] Jonathan Wolf Mueller, et al. J Clin Endocrinol Metab. Steroid Sulfation in Adrenal Tumors
[3] Sleyman Gnal, et al. J Biol Chem. Sulfation pathways from red to green
[4] Vitor H Pomin. Eur J Med Chem. Sulfated glycans in inflammation
| Related PARP Products |
|---|
| 2-Methylquinazolin-4-ol
2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with IC50 of 0.20 mM. |
| DPQ
DPQ is a potent PARP-1 inhibitor. |
| OUL232
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. |
| AZ3391
AZ3391 is a potent inhibitor of PARP. |
| PARP1-IN-5
PARP1-IN-5 is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). |
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