About 2 results found for searched term "NLRP3/AIM2-IN-2" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M45373 | NLRP3/AIM2-IN-2 | NLR |
| NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM. | ||
| M45372 | NLRP3/AIM2-IN-3 | NLR |
| NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 μM. | ||
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