About 11 results found for searched term "ML-18" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1828 | Tandutinib | FLT3 |
| MLN518, CT53518 | ||
| Tandutinib (MLN518, CT53518) is an orally active multitargeted tyrosine kinase inhibitor of FLT3 (IC50 = 0.22 μM), and it also inhibits c-Kit and PDGFR with IC50 values of 0.17 μM and 0.20 μM, respectively. Tandutinib has the ability to cross the blood-brain barrier. | ||
| M6971 | ML 218 hydrochloride | Others |
| ML 218 hydrochloride is a ca 2+ channel blocker (T-type). | ||
| M8912 | ML-18 | Bombesin Receptor |
| ML18 is Bombesin receptor subtype 3 (BRS-3) antagonist (IC50 = 4.8 μM). | ||
| M13650 | ML-60218 | DNA/RNA Synthesis |
| ML-60218 is a broad-spectrum RNA pol III inhibitor, with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. | ||
| M13758 | MLCK inhibitor peptide 18 | Myosin |
| MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations. | ||
| M14901 | Tandutinib hydrochloride | FLT3 |
| MLN518 hydrochloride; CT53518 hydrochloride | ||
| Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. | ||
| M29031 | ML418 | Potassium Channel |
| ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker. ML418 inhibits Kir7.1 with an IC50 value of 0.31 μM. ML418 can be used for the research of neurological, cardiovascular, endocrine and muscle disorders. | ||
| M45102 | ML188 | Anti-infection |
| ML188 is a first-in-class probe and also a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. antiviral activity. | ||
| M55658 | ML-184 | GPR/FFAR |
| CID2440433; ML184 | ||
| ML-184 (CID2440433) is a selective GPR55 agonist with an EC50 of 250 nM and exhibits >100-fold selectivity for GPR55 over GPR35, CB1 and CB2. ML-184(CID2440433) increases proliferation of neural stem cells and promotes neuronal differentiation in vitro. | ||
| M56452 | ML218 hydrochloride | Calcium Channel |
| ML218 hydrochloride is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. | ||
| M55757 | ML318 | Antibiotic |
| ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. | ||
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