About 6 results found for searched term "MAP4" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6940 | MAP4 | Others |
| MAP4 is a potent group II mGlu agonist. Also specific group III mGlu antagonist. | ||
| M7249 | SB 203580 hydrochloride | p38 MAPK |
| Adezmapimod hydrochloride ; RWJ 64809 hydrochloride | ||
| SB 203580 hydrochloride is a selective inhibitor of p38 MAPK; water-soluble. | ||
| M30216 | MAP4343 | Microtubule |
| MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents. | ||
| M42132 | TNIK&MAP4K4-IN-1 | MAPKAPK2/MAP3K/MAP4K |
| TNIK&MAP4K4-IN-1 is a dual inhibitor of TNIK and MAP4K4/HGK with IC50s of 1.29 nM and <10 nM, respectively, in human hepaticstellate cell LX-2. | ||
| M54852 | MAP4K4-IN-3 | MAPKAPK2/MAP3K/MAP4K |
| MAP4K4-IN-3 (Compound 17) | ||
| MAP4K4-IN-3 is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, and an IC50 of 470 nM in cell assay. | ||
| M55626 | INS018 055 | MAPKAPK2/MAP3K/MAP4K |
| TNIK&MAP4K4-IN-2; INS018_055 | ||
| INS018 055 is a TNIK and MAP4K4 inhibitor with IC50 values of 12-120 nM, respectively. INS018 055 exhibits anti-fibrotic activity across different organs in vivo through oral, inhaled or topical administration. INS018 055 possesses anti-inflammatory effects in addition to its anti-fibrotic profile, validated in multiple in vivo studies. | ||
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