About 17 results found for searched term "MALT1" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3639 | MALT1 inhibitor (MI-2) | MALT1 |
| ABM-3912; MI-2 | ||
| MALT1 inhibitor is an irreversible MALT1 inhibitor with IC50 of 5.84 μM. | ||
| M14462 | MLT-748 | MALT1 |
| MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM. | ||
| M19432 | Maltose (High purity) | Metabolite/Endogenous Metabolite |
| Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria. | ||
| M20826 | JNJ-67856633 | MALT1 |
| JNJ-6633 | ||
| Safimaltib (JNJ-67856633) is an orally active, first-in-class, potent, selective mucosa-associated lymphoid tissue protein 1 (MALT1) allosteric inhibitor for studies related to chronic lymphocytic leukemia (CLL). | ||
| M21291 | MLT-985 | MALT1 |
| MLT-985 is a highly selective inhibitor of MALT1 conformation with an IC50 value of 3 nM. | ||
| M22509 | Z-VRPR-FMK | MALT1 |
| Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression. | ||
| M29223 | MLT-747 | MALT1 |
| MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM. | ||
| M39786 | Isomaltotriose | Others |
| Isomaltotriose is a sugar from enzymic hydrolyzates of the dextran from Leuconostoc mesenteroides NRRL B-512. | ||
| M43924 | MLT-943 | MALT1 |
| MLT-943 is a potent, selective, and orally active inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1) that inhibits IL-2 secretion in PBMC or whole blood with IC50 values of 0.07-0.09 μM and 0.6-0.8 μM, respectively.In addition, MLT-943 possesses anti-inflammatory activity and can be used in studies of FcgR-mediated inflammation . | ||
| M43925 | ONO-7018 | MALT1 |
| ONO-7018 is a MALT1 inhibitor for studies related to non-Hodgkin's lymphoma, chronic lymphocytic leukemia. | ||
| M43926 | ABBV-525 | MALT1 |
| ABBV-525 is a MALT1 inhibitor for studies related to B-cell chronic lymphocytic leukemia, diffuse large B-cell lymphoma. | ||
| M43927 | SGR-1505 | MALT1 |
| SGR1505 | ||
| SGR-1505 is an oral potent small molecule allosteric inhibitor of MALT1 that inhibits MALT1 enzymatic activity and demonstrates anti-proliferative activity in ABC-DLBCL cell lines, both BTKi-sensitive (OCI-LY10) and BTKi-resistant (OCI-LY3). SGR-1505 can be used in studies related to B-cell tumors. | ||
| M43928 | MPT-0118 | MALT1 |
| MPT-0118 is an S-enantiomer of methylpiperazine and a MALT1 inhibitor that can be used in studies related to B-cell tumors. | ||
| M45232 | Mepazine | MALT1 |
| Pecazine | ||
| Mepazine is a potent and selective inhibitor of MALT1 protease, with IC50s of 0.83 and 0.42 μM for inhibition of full-length GSTMALT1 and GSTMALT1 325-760 segments, respectively, and also affects the viability of ABC-DLBCL cells by enhancing apoptosis. Mepazine also affects the viability of ABC-DLBCL cells by enhancing apoptosis. | ||
| M52575 | Val-Arg-Pro-DL-Arg-Fluoromethylketone | MALT1 |
| Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. | ||
| M55349 | n-Dodecyl α-D-maltoside | Others |
| n-Dodecyl α-D-maltoside is a nonionic detergent commonly used to solubilize integral membrane proteins and protein complexes. It has a critical micelle concentration (CMC) of 0.15 mM. n-Dodecyl α-D-maltoside has been used to solubilize photosystem I (PSI) and PSII complexes from plant thylakoid membranes, as well as intact grana. | ||
| M56713 | Mepazine hydrochloride | MALT1 |
| Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. | ||
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