About 9 results found for searched term "L-NIO" (0.055 seconds)
Cat.No. | Name | Target |
---|---|---|
M10186 | Leniolisib | PI3K |
CDZ173 | ||
Leniolisib (CDZ173) is a first-in-class (first-in-class), potent, selective PI3Kδ inhibitor with an IC50 value of 11 nM. Leniolisib has the potential for immunodeficiency disorders treatment. | ||
M14100 | L-NIO dihydrochloride | NO Synthase |
L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. | ||
M18728 | Geranylgeraniol | Others |
Geranylgeraniol | ||
M20442 | Nanofin | AChR/AChE |
2,6-Dimethylpiperidine; Lupetidine; Naniopinum | ||
Nanofin is a ganglion blocker alkaloid having nicotinic acetylcholine receptor antagonist action. It has antihypertensive effect used for mild to moderate hypertension. | ||
M40079 | Neosolaniol | Others |
Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp. Neosolaniol evokes robust anorectic response. | ||
M42008 | L-NIO | NO Synthase |
L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively. | ||
M42012 | Vinyl-L-NIO hydrochloride | NO Synthase |
Vinyl-L-NIO hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. | ||
M43397 | Leniolisib phosphate | PI3K |
Leniolisib (CDZ173) phosphate is a first-in-class, potent and selective PI3Kδ inhibitor with an IC50 value of 11 nM.Leniolisib is more selective for PI3K-δ than PI3K-α (28-fold), PI3K-β (43-fold) and PI3K-γ (257-fold). -γ (257-fold). In a cellular assay, Leniolisib decreased pAKT pathway activity and inhibited the proliferation and activation of B and T cell subsets. | ||
M57792 | 4-trimethylammoniobutanal | Others |
4-trimethylammoniobutanal |
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