About 7 results found for searched term "L-Kynurenine" (0.266 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9723 | L-Kynurenine | Aryl hydrocarbon Receptor |
| L-Kynurenine is an aryl hydrocarbon receptor agonist. | ||
| M15049 | 3-Hydroxykynurenine | Metabolite/Endogenous Metabolite |
| 3-Hydroxy-DL-kynurenine | ||
| 3-Hydroxykynurenine is an active metabolite of tryptophan. | ||
| M3736 | Ro 61-8048 | Others |
| Ro 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 of 37 nM that increases kynurenic acid levels and reduces extracellular glutamate in the brain. | ||
| M8075 | PF-04859989 hydrochloride | Others |
| PF-04859989 is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid, which has been implicated in several psychiatric and neurological disorders, including schizophrenia and bipolar disorder, and thought to impair cognitive function. | ||
| M10243 | D-Kynurenine | Aryl hydrocarbon Receptor |
| D-kynurenine is a metabolite of D-tryptophan, which can be used as a biological precursor of KYNA and 3-hydroxykynurenine. | ||
| M28503 | UPF-648 sodium salt | Others |
| UPF-648 sodium salt is a potent kynurenine 3-monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 ± 10% KMO inhibition); ineffective at blocking KAT activity. | ||
| M45057 | Recombinant Human IDO Protein (E.coli, N-6His) | Cytokines and Growth Factors |
| Indoleamine 2,3-dioxygenase | ||
| Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. | ||
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