About 6 results found for searched term "Keap1-Nrf2-IN-1" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14593 | Keap1-Nrf2-IN-1 | Keap1-Nrf2 |
| Keap1-Nrf2-IN-1 is a Keap1 (Kelch-like ECH-associated protein 1)-Nrf2 (nuclear factor erythroid 2-related factor 2) protein-protein interaction inhibitor, and with an IC50 of 43 nM for Keap1 protein. | ||
| M42729 | Keap1-Nrf2-IN-15 | Keap1-Nrf2 |
| Keap1-Nrf2-IN-15 is a potent Keap1-Nrf2 protein-protein interaction inhibitor with IC50s of 77 nM and 2.5 nM in FP assay and TR-FRET assay, respectively. | ||
| M42735 | Keap1-Nrf2-IN-16 | Keap1-Nrf2 |
| Keap1-Nrf2-IN-16 is a biological active peptide. | ||
| M14594 | KI696 | Keap1-Nrf2 |
| KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction. | ||
| M28606 | CPUY192018 | Others |
| CPUY192018 is a potent Keap1-Nrf2-ARE inhibitor with an IC50 of 0.63 µM. CPUY192018 exhibits induction of Nrf2-dependent gene NQO1 at 100 µM. | ||
| M30231 | Tricetin | Apoptosis |
| Tricetin is a potent competitive inhibitor of the Keap1-Nrf2 Protein Protein Interaction (PPI). Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway. | ||
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