About 6 results found for searched term "INH154" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20840 | INH154 | Others |
| INH154 is a potent inhibitor of Nek2 and Hec1 binding. NH154 binds to Hec1, thus blocking Hec1 phosphorylation by NEK2, and kills cancer cells at the nanomolar range. | ||
| M4403 | Groenlandicine | Topoisomerase |
| Groenlandicine is a proto berberine alkaloid isolated from coptis chinensis. Groenlandicine has moderate inhibition of human recombinant aldose reductase (HRAR) with an IC50 value of 154.2 μM. Groenlandicine induces DNA cleavage mediated by topoisomerase I. | ||
| M20833 | Vodobatinib (K0706) | Src-bcr-Abl |
| SCO-088, SUN K706, SUN-K0706 | ||
| Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively. | ||
| M22050 | CCT251545 | Wnt/beta-catenin |
| CCT251545 is an orally active, potent WNT inhibitor with an IC50 value of 5 nM for WNT inhibition in 7dF3 cells.In addition, CCT251545 is a selective chemical probe for studies related to the roles of CDK8 and CDK19 in human diseases. | ||
| M25497 | (Rac)-BIO8898 | TNF Receptor |
| (Rac)-BIO8898 is a CD40-CD154 co-stimulatory interaction inhibitor. (Rac)-BIO8898 inhibits CD154 binding to CD40-Ig with an IC50 of 25 μM. | ||
| M28810 | Stafib-1 | STAT |
| Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
