About 30 results found for searched term "HR1" (0.026 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5477 | Carbazochrome sodium sulfonate (AC-17) | Adrenergic Receptor |
| AC-17 | ||
| Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids. | ||
| M5549 | Danthron | AMPK |
| Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone | ||
| Danthron functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a synthetic anthraquinone derivative, currently used as an antioxidant in synthetic lubricants, in the synthesis of antitumor agents, as a fungicide and as an intermediate for making dyes. | ||
| M5775 | Metaxalone | Others |
| AHR438; NSC170959 | ||
| Metaxalone(AHR438; NSC170959) has muscle relaxation function and is an MOR agonist. | ||
| M6289 | Erythromycin cyclocarbonate | Antibiotic |
| Erythromycin cyclic carbonate; Erythromycin A 11,12-carbonate | ||
| Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome. | ||
| M6819 | IHR 1 | Others |
| IHR 1 is a potent Smo antagonist. | ||
| M9771 | TRAP-6 | Peptides |
| Thrombin Receptor Activator Peptide 6; PAR-1 agonist peptide | ||
| TRAP-6 (Thrombin Receptor Activator Peptide 6) is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. | ||
| M10445 | Fluzoparib (SHR3162) | PARP |
| SHR3162; Fuzuopali; Fuzuloparibum | ||
| Fluzoparib (SHR3162) is an effective oral active PARP1 inhibitor (IC50=1.46±0.72 nM) with superior antitumor activity. Fluzoparib selectively inhibited the proliferation of homologous recombination repair (HR) deficient cells and sensitized HR deficient cells to cytotoxic drugs. Fluzoparib has good pharmacokinetic properties in vivo and can be used in cancer research. | ||
| M13726 | Chroman 1 | ROCK |
| Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM. | ||
| M13781 | Dihydrorhodamine 123 | Fluorescent Dye |
| DHR 123 | ||
| Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λex=488 nm, λem=525 nm). | ||
| M14140 | Pyrotinib dimaleate | EGFR/HER2 |
| SHR-1258 dimaleate | ||
| Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively. | ||
| M14824 | GRF (1-29) amide (rat) | Peptides |
| rGHRH(1-29)NH2 | ||
| GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion. | ||
| M16206 | Chrysophanol 1-O-glucoside | Anthraquinones |
| Chrysophanol 1-O-glucoside | ||
| M16995 | 2-C-Methyl-D-erythrono-1,4-lactone | Others |
| 2-C-Methyl-D-erythrono-1,4-lactone | ||
| M17369 | erythro-1-(4-Hydroxy- 3-methoxyphenyl)propane-1,2-diol | Phenylpropanoids |
| erythro-1-(4-Hydroxy- 3-methoxyphenyl)propane-1,2-diol | ||
| M17372 | erythro-1-(4-Hydroxyphenyl)propane-1,2,3-triol | Phenylpropanoids |
| erythro-1-(4-Hydroxyphenyl)propane-1,2,3-triol | ||
| M17373 | threo-1-(4-Hydroxyphenyl)propane-1,2,3-triol | Phenylpropanoids |
| threo-1-(4-Hydroxyphenyl)propane-1,2,3-triol | ||
| M17385 | erythro-1-Phenylpropane-1,2-diol | Phenylpropanoids |
| erythro-1-Phenylpropane-1,2-diol | ||
| M17391 | threo-1-C-Syringylglycerol | Phenylpropanoids |
| threo-1-C-Syringylglycerol | ||
| M17924 | 9,10-Anthracenedione, 3-[[6-O-acetyl-2-O-(6-deoxy--L-mannopyranosyl)--D-glucopyranosyl]oxy]-1,6-dihydroxy-2-methyl- | Others |
| 9,10-Anthracenedione, 3-[[6-O-acetyl-2-O-（6-deoxy--L-mannopyranosyl）--D-glucopyranosyl]oxy]-1,6-dihydroxy-2-methyl- | ||
| M17929 | 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone-3-O-α-L-rhamnopyranosyl-(1->2)-β-D-glucopyranoside | Others |
| 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone-3-O-α-L-rhamnopyranosyl-（1->2）-β-D-glucopyranoside | ||
| M17950 | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione；Obtusin | Monoamine Oxidase |
| 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione；Obtusin | ||
| M18111 | Chrysophanol 1-O-β-gentiobioside | Monoamine Oxidase |
| Chrysophanol 1-O-β-gentiobioside | ||
| M20681 | Sphingosine | Metabolite/Endogenous Metabolite |
| D-erythro-Sphingosine; erythro-C18-Sphingosine | ||
| Sphingosine (D-erythro-Sphingosine, Erythrosphingosine) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid. | ||
| M20844 | Bexagliflozin (EGT1442) | SGLT |
| EGT-0001442, THR-1442 | ||
| Bexagliflozin (EGT1442, EGT-0001442, THR-1442) is a potent and selective SGLT2 inhibitor with an IC50 of 2 nM. | ||
| M20861 | Somatostatin Acetate | Somatostatin Receptor |
| Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(Cys3-Cys14) | ||
| Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. | ||
| M21079 | Loxoprofenol-SRS tromethamine | COX |
| HR1405–01 | ||
| Loxoprofenol-SRS tromethamine (HR1405-01) is an intravenous NSAID with good anti-inflammatory and analgesic activity. | ||
| M21134 | SHR168442 | ROR |
| SHR168442 is a modulator of RORγ with an IC50 value of 0.035 μM. It can be used as a skin-restricted topical compound for the study of psoriasis. | ||
| M21227 | HR011303 | URAT1 |
| HR011303 is a novel and highly selective urate transporter 1 (URAT1) inhibitor. | ||
| M24808 | Camrelizumab | PD-1/PD-L1 |
| SHR-1210 | ||
| Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al. | ||
| M25031 | Adebrelimab | PD-1/PD-L1 |
| SHR-1316 | ||
| Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 (PD-1/PD-L1) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC). | ||
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