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SHR168442 is a modulator of RORγ with an IC50 value of 0.035 μM. It can be used as a skin-restricted topical compound for the study of psoriasis.
| Molecular Weight | 532.43 |
| Formula | C23H25Cl2F2N3O3S |
| CAS Number | 2382961-86-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related ROR Products |
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| ASN06917370
ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. |
| JTE-151
JTE-151 is a RORγ inhibitor that suppresses overactive immune responses by inhibiting RORγ associated with Th17 cell activation.JTE-151 can be used in studies related to autoimmune diseases. |
| SAR-441169
SAR-441169 is a RORγt inverse agonist that can be used in studies related to psoriasis. |
| GRC-39815
GRC-39815 is a RORγt inverse agonist that can be used in studies related to chronic obstructive pulmonary disease. |
| RORγ antagonist 1
RORγ antagonist 1, a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM). |
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