About 30 results found for searched term "HA5" (0.036 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1769 | PHA-739358 (Danusertib) | Aurora Kinase |
| Danusertib | ||
| PHA-739358 (Danusertib) is a small molecule with low nanomolar activity against all aurora kinases (AKs) with IC50 value of 13 nM for aurora-A and 79 nM for aurora-B respectively. | ||
| M1899 | PHA-665752 | c-Met |
| PHA-665752 is a selective small molecule c-MET inhibitor (Ki of 4 nM, IC50 of 9 nM). | ||
| M3519 | PHA-848125 | CDK |
| Milciclib | ||
| PHA-848125 is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. | ||
| M3751 | Losmapimod | p38 MAPK |
| GW-856553X; GSK-AHAB; SB856553 | ||
| Losmapimod (GW856553) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. | ||
| M3942 | Cephalotaxine | Anti-infection |
| (-)-Cephalotaxine; ZINC19795976 | ||
| Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia. | ||
| M4463 | Abametapir | MMP |
| HA-44; BRN 0123183; 5,5′-Dimethyl-2,2′-dipyridyl | ||
| Abametapir (HA-44, BRN 0123183) is an inhibitor of metalloproteinases critical for louse survival and egg development. | ||
| M4623 | 3β-acetoxy-eupha-7-25-dien-24(R)-ol | Others |
| 3β-acetoxy-eupha-7-25-dien-24(R)-ol | ||
| M4822 | Eltrombopag Olamine | Thrombopoietin/Thrombin |
| Eltrombopag diethanolamine salt; SB-497115GR | ||
| Eltrombopag olamine is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. | ||
| M6075 | HA15 | Others |
| HA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors. | ||
| M8055 | PHA-543613 | Others |
| PHA-543613 is a potent selective α7 nAChR agonist. | ||
| M8253 | Mifamurtide | Others |
| CGP-19835; MTP-PE; MTP-cephalin; CGP19835; L-MTP-PE; MLV19835 | ||
| Mifamurtide (Muramyl tripeptide phosphatidylethanolamine; MTP-cephalin; MTP-PE) is a synthetic, lipophilic analog of muramyl dipeptide. | ||
| M9608 | APX-115 | NADPH Oxidase |
| Ewha-18278; APX-115 free base | ||
| APX-115 is a potent, orally active inhibitor of pan NADPH oxidase (Nox) with Ki of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. | ||
| M13644 | Cytidine-5'-triphosphate | DNA/RNA Synthesis |
| Cytidine triphosphate; 5'-CTP | ||
| Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. | ||
| M14401 | Phosphorylethanolamine | Metabolite/Endogenous Metabolite |
| Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine | ||
| Phosphorylethanolamine is an endogenous metabolite. | ||
| M14409 | Cytidine-5'-triphosphate disodium | Metabolite/Endogenous Metabolite |
| Cytidine triphosphate disodium; 5'-CTP disodium | ||
| Cytidine-5'-triphosphate disodium is an endogenous metabolite. | ||
| M15104 | ADP | Metabolite/Endogenous Metabolite |
| Adenosine diphosphate; Adenosine 5'-diphosphate | ||
| ADP (Adenosine 5'-diphosphate) is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPase. Is necessary for the flow of energy in living cells. | ||
| M16352 | 3,10-Dihydroxydielmentha-5,11-diene-4,9-dione | Diterpenoids |
| 3,10-Dihydroxydielmentha-5,11-diene-4,9-dione | ||
| M17955 | (13alpha,14beta,17alpha,20S)-5alpha-Lanosta-8,24-Dien-3beta-Ol | Others |
| (13alpha,14beta,17alpha,20S)-5alpha-Lanosta-8,24-Dien-3beta-Ol | ||
| M18107 | 6α-chloro-5β-hydroxywithaferin A | Antibiotic |
| 6alpha-Chloro-5beta-hydroxywithaferin A | ||
| 6α-chloro-5β-hydroxywithaferin A is a withanolide that can be isolated from W. somnifera. W. somnifera has antioxidant, anti-inflammatory, immunomodulatory, anticarcinogenic, antibacterial antiparkinsonism and antistress properties. | ||
| M20941 | Raloxifene | Estrogen Receptor |
| Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129 | ||
| Raloxifene is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. | ||
| M24656 | Zolimomab aritox | Others |
| H65-ricin A chain immunotoxin, H65-RTA | ||
| Zolimomab aritox (H65-RTA) is an immunocoupling compound consisting of a ricin (RTA) chain, a ribosomal inhibitory protein, coupled to a monoclonal antibody (H65) against the pan-T-cell antigen CD5. Zolimomab aritox has anticancer activity and can be used in cutaneous T-cell lymphoma studies. | ||
| M24816 | Gedivumab | Anti-infection |
| MHAA4549A; RG7745 | ||
| Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody that targets influenza A virus (IAV) with high specificity and binds to the highly conserved stem region of the IAV haemagglutinin protein, thereby preventing haemagglutinin maturation and blocking haemagglutinin-mediated membrane fusion in the intranucleosome. Gedivumab can be used in IAV infection disease studies. | ||
| M24817 | Lesofavumab | Anti-infection |
| MHAB5553A; RG70026 | ||
| Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody. | ||
| M24823 | Sirtratumab | Others |
| AGS15C; Ha15-10ac12; Ha15-10ac12.1 | ||
| Sirtratumab is a humanized Igγ2 monoclonal antibody against SLIT and NTRK-like family 6 (Slitrk6). Sirtratumab can be used in research of cancer. | ||
| M28265 | Delavirdine | HIV Protease |
| U 90152; BHAP-U 90152 | ||
| Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26 μM) over DNA polymerase α (IC50=440 μM) and polymerase δ (IC50>550 μM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs. | ||
| M30423 | Thalidomide-5-OH | Ligand for E3 Ligase |
| Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs. | ||
| M30986 | Citicoline | Apoptosis |
| Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine | ||
| Citicoline (Cytidine diphosphate-choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects. | ||
| M41060 | HA5 | Antibiotic |
| HA5 inhibits Streptococcus mutans biofilm with an IC50 value of 6.42 μM, without affecting its growth. | ||
| M43418 | Thalidomide-5-propargyl | Ligand for E3 Ligase |
| Thalidomide-5-propargyl is a propargyl-modified Thalidomide, that acts as a Cereblon ligand to recruit CRBN proteins. | ||
| M44525 | Isorhamnetin 3,5-O-diglucoside | Others |
| Isorhamnetin 3,5-O-diglucoside | ||
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