About 8 results found for searched term "Gamma-secretase" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7934 | MDL 28170 | Gamma-secretase/Beta-secretase |
| Calpain Inhibitor III | ||
| Mdl-28170 (Calpain Inhibitor III) is a potent, selective, membrane-permeable Inhibitor of cysteine protease (Calpain Inhibitor III) that can quickly cross the blood-brain barrier after systemic administration. Mdl-28170 also blocks gamma-secretase. | ||
| M11280 | Z-Ile-Leu-aldehyde | Notch |
| Z-IL-CHO; GSI-XII; γ-Secretase inhibitor XII | ||
| Z-ile-leu-aldehyde (Z-IL-Cho) is a potent and competitive peptide-aldehyde inhibitor of gamma-secretase and Notch. | ||
| M14574 | Notch inhibitor 1 | Notch |
| BMS-986115 | ||
| Notch inhibitor 1 is a potent inhibitor of Notch, with IC50 values of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively.In addition, Notch inhibitor 1 is also an inhibitor of gamma-secretase, which can be used in sclerofibrosarcoma-related studies. | ||
| M14583 | E 2012 | Gamma-secretase/Beta-secretase |
| E2012 | ||
| E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. | ||
| M21196 | FRM-024 | Others |
| FRM-024 is a potent CNS-permeable gamma-secretase modulator and a candidate for familial Alzheimer's disease. | ||
| M21274 | RO7185876 | Gamma-secretase/Beta-secretase |
| RO7185876 is a gamma-secretase modulator (GSM) for the study of Alzheimer's disease. | ||
| M49494 | BMS-932481 | Gamma-secretase/Beta-secretase |
| BMS-932481 is a small molecule gamma-secretase (γ-secretase) inhibitor that can be used in Alzheimer's disease related studies. | ||
| M53422 | Amyloid 17-42 | Apoptosis |
| Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). | ||
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