GLP-26 - Search Results | AbMole BioScience

About 4 results found for searched term "GLP-26" (0.146 seconds)

Cat.No.	Name	Target
M55579	GLP-26	Anti-infection
	GLP26
	GLP-26 is an HBV capsid assembly modulators (CAM), inhibits HBV DNA replication (IC50=3 nM) in Hep AD38 system, and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools.
M6466	AS 1269574	GPR/FFAR
	AS1269574 is a potent, orally active GPR119 agonist with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates the TRPA1 cation channel and stimulates glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induced pancreatic β cells to secrete glucose-dependent insulin only under high glucose conditions. AS1269574 has potential for type 2 diabetes research.
M29593	GLP-1 receptor agonist 9	GLP Receptor
	GLP-1 receptor agonist 9 is a GLP-1 receptor agonist, example 7, extracted from WO2020234726 A1.
M55684	GLP-1R agonist	Glucagon Receptor
	GLP-1R agonist DMB; Compound 2
	GLP-1R agonist is a potent GLP-1R (glucagon-like peptide 1 receptor) agonist, with KB of 26.3 nM for the recombinant human receptor. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight.