About 21 results found for searched term "G12" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3663 | K-Ras(G12C) inhibitor 9 | Ras |
| K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). | ||
| M8230 | 2002-G12 | Others |
| 2002-G12 binds Aβ peptide and was shown to inhibit Aβ42-induced killing of PC12 cells. | ||
| M11233 | Recombinant Human KRAS(G12C, His, E.coli) | Cytokines and Growth Factors |
| Ki-Ras; c-K-ras; KRAS2 | ||
| Recombinant Human KRAS(G12C, His, E.coli) was produced by the Escherichia coli expression system, and the target gene encoding Thr2-CYS185 (Gly12Cys) was expressed by 6His tag at the N-terminal. | ||
| M9300 | AG 126 | ERK |
| AG126; Tyrphostin AG 126 | ||
| AG 126 is a cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages. | ||
| M11234 | Recombinant Human KRAS (G12D, E. coli, His) | Cytokines and Growth Factors |
| Recombinant Human KRAS G12D (E. coli, His) | ||
| Recombinant Human KRAS (G12D, E. coli, His) was produced by the Escherichia coli expression system and expressed with the n-terminal 6His label. | ||
| M13988 | GLPG1205 | Others |
| GLPG1205 is potent, selective and orally active GPR84 (a G-protein-coupled receptor) antagonist with a favorable PK/PD profile. GLPG1205 has anti-inflammatory activity and is used for the treatment of pulmonary fibrosis. | ||
| M20595 | K-Ras(G12C) inhibitor 12 | ROCK |
| K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). | ||
| M20596 | K-Ras(G12C) inhibitor 6 | ROCK |
| K-Ras(G12C) inhibitor 6 is an allosteric, and selective inhibitor of oncogenic K-Ras(G12C). | ||
| M24784 | Faralimomab | Others |
| 64G12 | ||
| Faralimomab (64G12) is an immunomodulator, and a murine anti-IFNA1 IgG1 mAb. | ||
| M41912 | PROTAC KRAS G12C degrader-2 | PROTAC |
| PROTAC KRAS G12C degrader-2 is a modulator of K-Ras protein hydrolysis. | ||
| M41920 | KRAS G12D modulator-1 | Ras |
| KRAS G12D modulator-1 is a potent KRAS G12D modulator with IC50 values of 1-10 μM for NEA-G12D, PPI-G12D, and p ERK-AGS, respectively. | ||
| M41925 | PROTAC KRAS G12C degrader-3 | Ras |
| PROTAC KRAS G12C degrader-3 is a potent KRAS G12C degrader for cancer research. | ||
| M41927 | KRAS G12C inhibitor 58 | Ras |
| KRAS G12C inhibitor 58 is a KRAS G12C inhibitor, used in cancer research. | ||
| M41933 | KRASG12C IN-2 | Ras |
| KRASG12C IN-2 is an orally active KRASG12C inhibitor. | ||
| M42117 | KRAS G12C inhibitor 61 | ERK |
| KRAS G12C inhibitor 61 inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. | ||
| M49938 | Glecirasib | Ras |
| JAB-21822; KRAS G12C inhibitor 36 | ||
| Glecirasib is a potent, irreversible, orally active KRAS G12C inhibitor for studies related to KRAS G12C-mediated cancers. | ||
| M50846 | KRAS G12D(8-16) | Others |
| KRAS G12D 8-16 is a mutant KRAS G12D 8-16 peptide. | ||
| M54284 | G12 | Others |
| G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). | ||
| M55018 | RMC-9805 | Ras |
| KRAS G12D inhibitor 18; Zoldonrasib | ||
| RMC-9805 (KRAS G12D inhibitor 18) is a first-in-class, orally active KRAS G12D inhibitor. RMC-9805 (KRAS G12D inhibitor 18) inhibits RAS signaling and induces apoptosis in KRAS G12D mutant cancer cells. | ||
| M56319 | K-Ras G12C-IN-3 | Ras |
| K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. | ||
| M57806 | KRAS G12C inhibitor 19 | Others |
| KRAS G12C inhibitor 19 | ||
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