About 5 results found for searched term "Fraxin" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4397 | Fraxin | PDE |
| Fraxoside | ||
| Fraxin is a glucoside of fraxetin, an O-methylated coumarin. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme. Fraxin was administered orally to rats to investigate its metabolism. | ||
| M4556 | Fraxinellone | PD-1/PD-L1 |
| Fraxinellone was isolated from the root bark of the brassica family Dictamnus dasycarpus. Fraxinellone is a PD-L1 inhibitor that inhibits HIF-1α synthesis without affecting HIF-1α degradation. Fraxinellone has potential for cancer immunity by targeting PD-L1. | ||
| M19353 | Fraxinol | Cytochrome P450 (e.g. CYP17) |
| Fraxinol is isolated from Lobelia chinensis. | ||
| M4396 | Fraxetin | Apoptosis |
| Fraxetin is separate from Cortex Fraxini. Fraxetin has anti-tumor, antioxidant and anti-inflammatory effects. Fraxetin can induce apoptosis. | ||
| M14849 | Esculetin | PI3K |
| Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. | ||
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