About 12 results found for searched term "F-ara-EdU" (0.148 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M57563 | F-ara-EdU | Others |
| F-ara-EdU | ||
| M1698 | Clofarabine | DNA/RNA Synthesis |
| Clolar, Evoltra | ||
| Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. | ||
| M2028 | Fludarabine | STAT |
| Fludara; NSC 118218; Fludarabinum; F-ara-A | ||
| Fludarabine (NSC 118218) is a STAT1 activation inhibitor and a DNA synthesis inhibitor. Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. Fludarabine markedly inhibited VSMC proliferation in cell culture. Fludarabine also induces significant reduction of STAT-1 phosphorylation, whereas it does not change JAK2 activation. Fludarabine exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. | ||
| M3315 | Thiabendazole | Mitochondrial Related |
| 2-(4-Thiazolyl)benzimidazole | ||
| Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property. | ||
| M4543 | Byakangelicin | Others |
| (Rac)-Byakangelicin is the racemate of Byakangelicin, which is mainly separated from the genus Angelica. Byakangelicin is an aldose reductase inhibitor with an IC50 value of 6.2 μM. | ||
| M4764 | taraxasteryl-acetate | Others |
| Taraxasteryl acetate was isolated from sagittal plasmodium and showed a broad spectrum of anti-inflammatory activity. Taraxasteryl acetate can reduce posterior claw edema induced by dextran, yeast glycan and arachidonic acid in rats. Taraxasteryl acetate can be used to study local inflammation. | ||
| M10640 | Uricase | Enzymes & Coenzymes |
| Uricase is a new type of uric acid-lowering compound, also known as Urate Oxidase, it is characterized by promoting the decomposition of uric acid, catalyzes the rapid oxidation of uric acid into allantoic acid, which is no longer reabsorbed and excreted by the renal tubules, thereby reducing the content of uric acid in the plasma. | ||
| M13886 | Fipexide | Adenylate Cyclase |
| FPX | ||
| Fipexide, a parachloro-phenossiacetic acid derivative. Fipexide (FPX) is a novel chemical inducer that promotes callus formation and shoot regeneration in plants. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. | ||
| M24997 | Tafolecimab | PCSK9 |
| IBI-306 | ||
| Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C and leads to a reduction in LDL-C levels. Tafolecimab may be used in studies of hypercholesterolaemia. | ||
| M28002 | Tenapanor hydrochloride | Na+/H+ Exchanger (NHE) |
| AZD1722 hydrochloride; RDX5791 hydrochloride | ||
| Tenapanor (AZD1722) hydrochloride is a first-in-class, potent, orally active sodium/hydrogen exchange isomer 3 (NHE3) inhibitor that reduces intestinal phosphate absorption primarily by decreasing passive paracellular phosphate flux. Tenapanor hydrochloride reduces intestinal absorption of phosphate by reducing passive paracellular phosphate flux. Tenapanor hydrochloride is used in studies related to chronic renal insufficiency, hyperphosphatemia, constipation, and irritable bowel syndrome. | ||
| M39004 | Cedrin | ROS |
| Cedrin is a natural flavonoid that can be found in Cedrus deodara. Cedrin protects PC12 cells against neurotoxicity induced by Aβ1-42. Cedrin can reduce reactive oxygen species overproduction, increase the activity of superoxide dismutase and decrease malondialdehyde content. | ||
| M40613 | Methylenedisalicylic acid | Anti-infection |
| MDSA | ||
| Methylenedisalicylic acid is a potent inhibitor of MarR family transcription factor A (MgrA) and Ser/Thr kinase (Stp1) that enhances SarA/MgrA phosphorylation through inhibition of Staphylococcus aureus Stp1, with an IC50 value of 9.68 ± 0.52 μM when acting on Stp1.In addition, Methylenedisalicylic acid can also be used as a lead compound in the study of methods to reduce staphylococcal toxicity. | ||
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