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Methylenedisalicylic acid is a potent inhibitor of MarR family transcription factor A (MgrA) and Ser/Thr kinase (Stp1) that enhances SarA/MgrA phosphorylation through inhibition of Staphylococcus aureus Stp1, with an IC50 value of 9.68 ± 0.52 μM when acting on Stp1.In addition, Methylenedisalicylic acid can also be used as a lead compound in the study of methods to reduce staphylococcal toxicity.
| Molecular Weight | 288.25 |
| Formula | C15H12O6 |
| CAS Number | 27496-82-8 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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