About 14 results found for searched term "EN460" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14697 | EN460 | Others |
| EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 (IC50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation. | ||
| M1784 | Icotinib | EGFR/HER2 |
| BPI-2009H | ||
| Icotinib (BPI-2009H) is a potent and novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC50 of 5 nM. Iconitib inhibits the proliferation of A431 and BGC-823 A549, H460 and KB cell lines with IC50s of 1, 4.06, 12.16, 16.08, 40.71 μM. | ||
| M3272 | Alendronate sodium hydrate | Others |
| Alendronate; MK 217; G-704650 Adronat | ||
| Alendronate is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM. | ||
| M13793 | MQAE | Fluorescent Dye |
| MQAE is a novel chloride ion fluorescence probe excited by ultraviolet light. MQAE, binding bromine ion as ligand, can be used to detect the activity of chloride. MQAE exhibits a reduction of fluorescence intensity with the increase of intracellular Cl- concentration. MQAE has a pH-independent fluorescence intensity basically at a Cl- concentration <50 nM. MQAE has high water solubility and cell permeability. Ex/Em=350/460 nm | ||
| M19198 | Gypsogenin | Others |
| Gypsogenin shows antiangiogenic activity and the significant cytotoxicity against H460. | ||
| M39654 | 7-Amino-4-methylcoumarin-3-acetic acid | Fluorescent Dye |
| 7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm). | ||
| M40416 | Jolkinol A | Others |
| Jolkinol A is a natural product that can be found in Euphorbia pubescens. Jolkinol A inhibits cell growth with GI50s of 95.3, 57.3, >100 µM for MCF-7, NCI-460, SF-268 cells, respectively. | ||
| M51678 | Ac-VEID-AMC | Fluorescent Dye |
| Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm). | ||
| M52532 | Z-LLF-CHO | Proteasome |
| Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (Ki = 460 nM). | ||
| M53104 | TAK-448 | Others |
| TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM. | ||
| M54313 | TAK-448 acetate | Others |
| TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM. | ||
| M54501 | MeOSuc-AAPV-AMC | Fluorescent Dye |
| MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm). | ||
| M55389 | HPTS | Fluorescent Dye |
| Fluorescent membrane-impermeant pH indicator; 8-Hydroxypyrene-1,3,6-trisulfonic acid | ||
| HPTS is a fluorescent membrane-impermeant pH indicator. Ex: 460nm, Em: 510nm | ||
| M58425 | Acridine Orange | Fluorescent Dye |
| Acridine Orange is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. | ||
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