EGFR-IN-81 - Search Results | AbMole BioScience

About 5 results found for searched term "EGFR-IN-81" (0.134 seconds)

Cat.No.	Name	Target
M42100	EGFR-IN-81	EGFR/HER2
	EGFR-IN-81 is an EGFR inhibitor.
M8758	GW806742X	Necroptosis
	GW806742X is an ATP site-targeing kinase inhibitor (IC50 in nM = 2/VEGFR2, 15/SRC, 47/C-FMS, 851/GSK3, 9016/ERBB2, 9120/FGFR) with potent antiproliferation activity against cancer cultures (IC50 in nM = 5/HUVEC-v, 424/HUVEC-b, 81/HEF, 453/MDA468, 470/A375P, 693/HT29, 734/PC3), GW806742X is now better known as Compound 1 for its anti-necroptosis activity via affinity interaction with ML
M9400	Firmonertinib mesylate	EGFR/HER2
	Alflutinib mesylate; AST2818 mesylate
	Firmonertinib (Alflutinib) mesylate is a potent, third generation EGFR inhibitor that targets both EGFR activating mutations and T790M thus leading to tumor growth inhibition. Firmonertinib (AST2818) has the potential for the research of non-small cell lung cancer (NSCLC).
M20715	CS-2660 (JNJ-38158471)	VEGFR/PDGFR
	CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.
M28801	NSC81111	EGFR/HER2
	NSC81111 is a potent and orally active EGFR-TK inhibitor with an IC50 of 0.15 nM. NSC81111 has anticaner effects.