About 22 results found for searched term "DG1" (0.154 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2059 | A-922500 | DGAT |
| DGAT-1 Inhibitor 4a; A922500 | ||
| A-922500 (DGAT-1 Inhibitor 4a) is a potent and selective DGAT-1 inhibitor with IC50 values of 9 and 22 nM at human and mouse DGAT-1 respectively. | ||
| M6669 | DG-041 | Prostaglandin Receptor |
| DG041 | ||
| DG-041 is a potent and selective EP3 antagonist; antiplatelet and antithrombotic. DG-041 inhibits PGE2 facilitation of platelet aggregation. DG-041 crosses the blood-brain barrier. | ||
| M7387 | TCS 5861528 | TRP Channel |
| Chembridge-5861528 | ||
| TCS 5861528 (Chembridge-5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively. | ||
| M8388 | T863 | DGAT |
| DGAT-1 inhibitor | ||
| T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. | ||
| M11255 | DG172 dihydrochloride | PPAR |
| DG172 dihydrochloride is a selective PPARβ/δ antagonist with an IC50 value of 27 nM. | ||
| M14291 | DGAT-1 inhibitor 2 | DGAT |
| DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents. | ||
| M15084 | Recombinant Mouse Sonic Hedgehog/Shh (E.coli) | Cytokines and Growth Factors |
| Sonic Hedgehog Protein; SHH; HHG-1; SHH | ||
| Recombinant mouse Sonic Hedgehog gene was prepared by escherichia coli expression system and the target gene encoding Cys25-Gly198 was expressed. Accession # : Q62226. | ||
| M15085 | Recombinant Mouse SHH (C25II, E.coli) | Cytokines and Growth Factors |
| Sonic Hedgehog Protein; SHH; HHG-1; SHH | ||
| Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. | ||
| M20763 | DGY-06-116 | Src-bcr-Abl |
| DGY-06-116 is an irreversible covalent and selective inhibitor of Src with IC50 of 2.6 nM. | ||
| M22144 | DG051 | Others |
| DG051 | ||
| M22173 | DGAT1-IN-1 | Others |
| DGAT1-IN-1 | ||
| M28855 | Dihomo-γ-linolenic acid | Metabolite/Endogenous Metabolite |
| DGLA; all-cis-8,11,14-Eicosatrienoic acid | ||
| Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system. | ||
| M29692 | Veldoreotide | Somatostatin Receptor |
| DG3173; PTR-3173 | ||
| Veldoreotide (DG3173) a somatostatin analogue, that can bind to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide inhibits growth hormone (GH) secretion in adenomas compared with Octreotide. Veldoreotide has the potential to be used as pain modulating agent[1] | ||
| M29706 | DGY-06-116 | Src-bcr-Abl |
| DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM. | ||
| M30575 | Migalastat hydrochloride | Others |
| DGJ; 1-Deoxygalactonojirimycin; GR181413A | ||
| Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. | ||
| M40491 | ENDG-4010 | Endothelin Receptor |
| ENDG-4010 is an endothelin receptor ETB agonist that can be used in tumor-related studies. | ||
| M41371 | DG1 | Others |
| DG1 is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. | ||
| M42327 | DGKζ-IN-1 | DGK |
| DGKζ-IN-1 is an inhibitor of DGKζ. | ||
| M43489 | MET/PDGFRA-IN-1 | c-Met |
| MET/PDGFRA-IN-1 is a MET and PDGFRA protein inhibitor (IC50: 36 μM for MET). | ||
| M51669 | Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10) | Others |
| Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10), a decapeptide containing a cyclic RGD active sequence, is an Integrin αIIbβ3 antagonist that inhibits platelet and Adhesion of proMMP-13. | ||
| M53703 | Psalmotoxin 1 | Sodium Channel |
| PcTx1; Psalmopoeus cambridgei toxin-1 | ||
| Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). | ||
| M54696 | DGY-09-192 | PROTAC |
| DGY-09-192 is a bivalent degrader that couples the pan-FGFR inhibitor BGJ398 to the CRL2VHL E3 ligase-recruiting ligand, which induces degradation of FGFR1/2 and largely avoids degradation of FGFR3/4.DGY-09-192 exhibits a nanomolar DC50 against both wild-type FGFR2 and several FGFR2 fusions. In addition, DGY-09-192 has antiproliferative activity in gastric and cholangiocarcinoma cells. | ||
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