About 6 results found for searched term "DC_05" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1725 | CUDC-305 | HSP |
| CUDC-305 is a heat shock protein 90 (HSP90) inhibitor of the novel imidazopyridine class. | ||
| M8558 | DC_05 | DNA Methyltransferase |
| DC_05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor that significantly inhibits cancer cell proliferation. | ||
| M10476 | GDC-0575 (ARRY-575) | Checkpoint |
| RG7741; ARRY575; AK-687476 | ||
| GDC-0575 (ARRY-575, RG7741) is a potent and selective oral inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. | ||
| M13621 | GDC-0575 dihydrochloride | Checkpoint |
| ARRY-575 dihydrochloride; RG7741 dihydrochloride | ||
| GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity. | ||
| M21393 | TCMDC-135051 | Others |
| TCMDC-135051 is a highly selective and potent inhibitor of the protein kinase PfCLK3 with low off-target toxicity.TCMDC-135051 prevents trophozoite to lytic transition, disrupts transcription and reduces transmission to mosquito vectors.TCMDC-135051 has antiparasitic activity (EC50=320 nM). | ||
| M27916 | GDC0575 hydrochloride | Checkpoint |
| ARRY-575 hydrochloride; RG7741 hydrochloride | ||
| GDC0575 (ARRY-575) hydrochloride is a highly-selective and orally active Chk1 (IC50=1.2 nM) inhibitor. GDC0575 (ARRY-575) hydrochloride can be used for colitis-associated cancer (CAC) and colitis research. | ||
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