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GDC-0575 dihydrochloride

Cat. No. M13621

All AbMole products are for research use only, cannot be used for human consumption.

GDC-0575 dihydrochloride Structure
Synonym:

ARRY-575 dihydrochloride; RG7741 dihydrochloride

Size Price Availability
5mg USD 210  USD210 Out of stock
10mg USD 300  USD300 Out of stock
25mg USD 520  USD520 Out of stock
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Quality Control & Documentation
Biological Activity

GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.

Chemical Information
Molecular Weight 451.19
CAS Number 1657014-42-0
Solubility (25°C) DMSO 65 mg/mL
Water 25 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Min Li, et al. Onco Targets Ther. GDC-0575, a CHK1 Inhibitor, Impairs the Development of Colitis and Colitis-Associated Cancer by Inhibiting CCR2 + Macrophage Infiltration in Mice

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Keywords: GDC-0575 dihydrochloride, ARRY-575 dihydrochloride; RG7741 dihydrochloride supplier, Checkpoint, inhibitors, activators

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