About 4 results found for searched term "Cyclophilin" (0.126 seconds)
Cat.No. | Name | Target |
---|---|---|
M1831 | Cyclosporine A | Immunology/Inflammation |
Ciclosporin A; CsA; Cyclosporin A; Antibiotic S 7481F1 | ||
Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. | ||
M7414 | TMN 355 | Cyclophilin |
TMN 355 is a cyclophilin A inhibitor. | ||
M21283 | ASP5286 | Cyclophilin |
ASP5286 is a novel non-immune cyclophilin inhibitor for the study of HCV. | ||
M29757 | CypD-IN-3 | Cyclophilin |
CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes. |
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