About 30 results found for searched term "Coumarin" (0.019 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2539 | Coumarin | Others |
| MIC | ||
| Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties. | ||
| M3306 | Daphnetin | PKC |
| 7,8-Dihydroxycoumarin | ||
| Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities. | ||
| M3928 | Scoparone | STAT |
| 6,7-Dimethoxycoumarin | ||
| Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. | ||
| M4478 | Psoralen | DNA/RNA Synthesis |
| Ficusin; Furocoumarin | ||
| Psoralen(Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity. | ||
| M4789 | Isoscopoletin | Anti-infection |
| 6-Hydroxy-7-methoxycoumarin | ||
| Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active ingredient in artemisia argyi leaves. Isoscopoletin showed significant inhibition of cell proliferation, with IC50 values of 4.0 μM and 1.6 μM against human CCRF-CEM leukemia cells and CEM/ADR5000 drug-resistant subline, respectively. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) has the activity of inhibiting HBV replication. | ||
| M4935 | 3-Cyano-7-ethoxycoumarin | Cytochrome P450 (e.g. CYP17) |
| 3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that generates blue fluorescent product upon enzyme cleavage. | ||
| M6182 | 7ACC1 | Monocarboxylate Transporter (MCT) |
| DEAC; Coumarin D 1421; D 1421 | ||
| 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. | ||
| M7781 | 7-Ethoxycoumarin | Others |
| Substrate for CYP2B6. | ||
| M9031 | 6-Methylcoumarin | Others |
| Toncarine | ||
| 6-Methylcoumarin belongs to the class of organic compounds known as coumarins and derivatives. | ||
| M9360 | Dicoumarol | PDK1 |
| Dicoumarin; Dicumarol | ||
| Dicoumarol (Dicoumarin) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively. | ||
| M9896 | Coumarin 6 | Fluorescent Dye |
| Coumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro. | ||
| M10257 | Glycycoumarin | Autophagy |
| Glycycoumarin is a bioactive coumarin of licorice, it inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress-mediated JNK and GSK-3-mediated mitochondrial pathway. | ||
| M11505 | 7-Amino-4-methylcoumarin | Serine/Threonine Protease |
| Coumarin 120; AMC | ||
| 7-amino-4-methylcoumarin (Coumarin 120) is used as a fluorescent probe for many serine proteases. Used for high performance liquid chromatographic labeling. | ||
| M11536 | Coumarin 2 | Others |
| 7-(Ethylamino)-4,6-dimethylcoumarin | ||
| 7-(ethylamino)-4,6-dimethylchromen-2-one | ||
| M14415 | Umbelliferone | Metabolite/Endogenous Metabolite |
| 7-Hydroxycoumarin; Hydrangin; NSC 19790 | ||
| Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. | ||
| M14508 | 3-Nitrocoumarin | Phospholipase |
| 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor. | ||
| M14674 | Coumarin-3-carboxylic Acid | Others |
| 2-Oxochromene-3-carboxylic acid | ||
| Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. | ||
| M16248 | 6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin | Coumarins |
| 6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin | ||
| M16249 | 6-(3-Methyl-2-oxobutyroyl)-7-methoxycoumarin | Coumarins |
| 6-(3-Methyl-2-oxobutyroyl)-7-methoxycoumarin | ||
| M16251 | 8-Geranyloxy-5,7-dimethoxycoumarin | Coumarins |
| 8-Geranyloxy-5,7-dimethoxycoumarin | ||
| M16255 | 7-Geranyloxy-6-methoxycoumarin | Coumarins |
| 7-Geranyloxy-6-methoxycoumarin | ||
| M16257 | 5,6,7,8-Tetramethoxycoumarin | Coumarins |
| 5,6,7,8-Tetramethoxycoumarin | ||
| M16263 | 5,7,8-Trimethoxycoumarin | Coumarins |
| 5,7,8-Trimethoxycoumarin | ||
| M16273 | 7-Prenyloxycoumarin | Coumarins |
| 7-Prenyloxycoumarin | ||
| M16282 | 7-Methoxycoumarin | Coumarins |
| 7-Methoxycoumarin | ||
| M18036 | 7-Hydroxy-4-(trifluoromethyl)coumarin | Others |
| 7-Hydroxy-4-(trifluoromethyl)coumarin | ||
| M18075 | 4-(Bromomethyl)-7-methoxy coumarin | Fluorescent Dye |
| 4-(Bromomethyl)-7-methoxy coumarin | ||
| M18136 | 5,7-Dihydroxy 4-methylcoumarin | Antifungal |
| 5,7-Dihydroxy 4-methylcoumarin | ||
| M18138 | 7-Geranyloxy-5-methoxycoumarin | Others |
| 7-Geranyloxy-5-methoxycoumarin | ||
| M18278 | 5,6,7-Trimethoxycoumarin | Others |
| 5,6,7-Trimethoxycoumarin | ||
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