About 9 results found for searched term "Compound E" (0.065 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5534 | Cortisone | GCR |
| 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E | ||
| Cortisone is a 21-carbon steroid hormone. Cortisone is one of the main hormones released by the adrenal gland in response to stress. | ||
| M7043 | NPS ALX Compound 4a dihydrochloride | Others |
| NPS ALX Compound 4a dihydrochloride is a potent and selective 5-HT 6 antagonist. | ||
| M9505 | Compound E | Gamma-secretase/Beta-secretase |
| GSI-XXI; γ-secretase inhibitor XXI; γ-Secretase-IN-1 | ||
| Compound E is a cell-permeable, potent, selective inhibitor of γ-secretase and Notch processing. | ||
| M20547 | Rabeprazole Related Compound E | Proton Pump |
| Rabeprazole thioether; Rabeprazole Sulfide | ||
| Rabeprazole Related Compound E is the active metabolite of Rabeprazole and an orally active proton pump inhibitor that inhibits gastric acid secretion by interacting with (H+/K+)-ATPase in gastric lining cells. In addition, Rabeprazole Related Compound E significantly inhibits the activity of Helicobacter pylori and can be used in studies related to various digestive disorders. | ||
| M20688 | B-Raf inhibitor 1 (Compound 13) dihydrochloride | Raf |
| B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and C-Raf, respectively. | ||
| M21681 | Compound 48/80 trihydrochloride | Phospholipase |
| C48/80 trihydrochloride | ||
| Compound 48/80 trihydrochloride is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways. | ||
| M55555 | PI3K/Akt/CREB activator 1 | PI3K |
| compound AE-18 | ||
| PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. | ||
| M56074 | NPS ALX Compound 4a dihydrochloride | 5-HT Receptor |
| NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM. | ||
| M58107 | PD-1/PD-L1-IN-9 | PD-1/PD-L1 |
| PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model. | ||
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